LASSI™ Publications

Digital LASSI-D

Digital Migration of a Validated Cognitive Challenge Test in Mild Cognitive Impairment: Convergence of the Loewenstein-Acevedo Scales for Semantic Interference and Learning (LASSI-L™) and the LASSI-D™ in older Participants with Amnestic MCI and Normal Cognition

Harvey et al., JMIR Preprints (2023)

Computerized LASSI-BC

The computerized LASSI-BC Test versus the Standard LASSI-L Paper-and-Pencil Version in Community-Based-Samples

Curiel-Cid et al. Advances in Alzheimer's Disease (2024)

LASSI-L as a Screening Instrument

Different aspects of failing to recover from proactive semantic interference predicts rate of progression from amnestic mild cognitive impairment to dementia

Curiel-Cid et al. Front Aging Neurosci. (2024)

LASSI-L as a Screening Instrument

Developing a Danish version of the LASSI-L test - reliability and predictive value in patients with mild cognitive impairment, mild dementia due to AD and subjective cognitive decline

Vogel et al. Aging, Neuropsychol Cogn. (2024)

LASSI-L as a Screening Instrument

Vulnerability to semantic and phonological interference in normal aging and amnestic mild cognitive impairment (aMCI)

Chasles et al. Neuropsychology (Feb. 2024)

LASSI-L as a Screening Instrument

Semantic intrusion errors are associated with plasma Ptau-181 among persons with amnestic mild cognitive impairment who are amyloid positive

Curiel-Cid et al. Front Neurol. (2023)

Computerized LASSI-BC

A Novel Computerized Cognitive Test for the Detection of Mild Cognitive Impairment and Its Association with Neurodegeneration in Alzheimer’s Disease Prone Brain Regions

Curiel et al., Advances in Alzheimer’s Disease (2023)

LASSI-L as a Screening Instrument

A Novel Computerized Cognitive Test for the Detection of Mild Cognitive Impairment and Its Association with Neurodegeneration in Alzheimer’s Disease Prone Brain Regions

Curiel et al., Advances in Alzheimer’s Disease (2023)

LASSI-L as a Screening Instrument

LASSI-L detects early cognitive changes in pre-motor manifest Huntington's disease: a replication and validation study

Sierra Luis A. et al., Frontiers in Neurology (2023)

Computerized LASSI-BC

A Novel Computerized Cognitive Stress Test to Detect Mild Cognitive Impairment.

Curiel-Cid, R. et al. The Journal of Prevention of Alzheimer’s Disease(2021)

LASSI-L in Longitudinal Prediction of Cognitive States

Intrusion Errors and Progression of Cognitive Deficits in Older Adults with Mild Cognitive Impairment and PreMCI States.

Crocco, et al. Dementia and geriatric cognitive disorders (2021)

LASSI-L as a Screening Instrument

A Brief Version of the LASSI-L Detects Prodromal Alzheimer's Disease States.

Crocco et al. Journal of Alzheimer’s Disease (2020)

Differential Diagnosis: LASSI-L and amyloid Markers of Mild Cognitive Impairment

The relationship of semantic intrusions to different etiological subtypes of MCI and cognitively healthy older adults.

Kitaigorodsky et al. Alzheimers’ and Dementia (2021)

Differential Diagnosis: LASSI-L and amyloid Markers of Mild Cognitive Impairment

A novel method of evaluating semantic intrusion errors to distinguish between amyloid positive and negative groups on the Alzheimer's disease continuum.

Curiel et al. Journal of Psychiatric Research (2020)

Differential Diagnosis - LASSI-L and Amyloid Markers of PreClinical AD

A Novel Cognitive Stress Test for the Detection of Preclinical Alzheimer’s Disease: Discriminative Properties and relation to Amyloid Load.

Loewenstein et. al American Journal of Geriatric Psychiatry (2016)

Differential Diagnosis - LASSI-L and Amyloid Markers of PreClinical AD

Utilizing Semantic Intrusions to Identify Amyloid Positivity in Mild Cognitive Impairment.

Loewenstein et. al Neurology (2018)

Differential Diagnosis - LASSI-L and Amyloid Markers of Mild Cognitive Impairment

Semantic Intrusions and Failure to Recover from Proactive Semantic Interference in Amnestic Mild Cognitive Impairment: Relationship to Amyloid Load and Cortical Thickness.

Curiel et. al Curr Alzheimer Res. (2018)

Differential Diagnosis - LASSI-L and Amyloid Markers of Mild Cognitive Impairment

A novel method of evaluating semantic intrusion errors to distinguish between amyloid positive and negative groups on the Alzheimer's disease continuum.

Curiel et. al Journal of Psychiatric Research (2018)

LASSI-L and MRI Markers of Mild Cognitive Impairment

Recovery from proactive semantic interference and MRI volume: A replication and extension study.

Loewenstein et. al J Alzheimers Dis. (2017)

LASSI-L and MRI markers of Mild Cognitive Impairment

Recovery from Proactive Semantic Interference in MCI and Normal Aging: Relationship to atrophy in brain regions vulnerable to Alzheimer’s Disease.

Loewenstein et. al J Alzheimers Dis. (2017)

LASSI-L and MRI Markers in PreMCI

A Novel Cognitive Assessment Paradigm to Detect Pre-Mild Cognitive Impairment (PreMCI) and the Relationship to Biological Markers of Alzheimer’s Disease.

Crocco et. al Journal of Psychiatric Research (2018)

LASSI-L in Middle Age Children of Late-onset AD Patients

Failure to recover from proactive semantic interference and abnormal limbic connectivity in asymptomatic, middle-aged offspring of patients with late-onset Alzheimer’s Disease.

Sanchez et. al J Alzheimers Dis. (2017)

LASSI-L in Middle Age Children of Late-onset AD Patients

Brain Structural and Amyloid Correlates of Recovery from Semantic Interference in Cognitively Normal Individuals with or without family History of Late-Onset Alzheimer’s Disease.

Abulafia et. al J Neuropsychiatry Clin Neurosci. (2019)

LASSI-L versus other Neuropsychological Measures

Comparison between FCSRT and LASSI-L to Detect Early Stage Alzheimer’s Disease.

Matias et. al J Alzheimers Dis. (2018)

LASSI-L versus other Neuropsychological Measures

Novel Cognitive Paradigms for the Detection of Memory Impairment in Preclinical Alzheimer’s Disease.

Loewenstein et. al Assessment (2018)

LASSI-L versus other Neuropsychological Measures

Individual cognitive and depressive traits associated with maternal versus paternal family history of Late-onset Alzheimer’s disease: Proactive semantic interference versus standard neuropsychological assessments.

Wilson et. al Personalized Medicine in Psychiatry (2018)

LASSI-L versus other Neuropsychological Measures

Memory Impairment in Relapsing-Remitting Multiple Sclerosis using a challenging semantic interference task.

Guiu et. al Front Neurol. (2020)

LASSI-L in Diverse Cultural Populations

Validation of the Spanish version of the LASSI-L for diagnosing mild cognitive impairment and Alzheimer’s Disease.

Guiu et. AlJ Alzheimers Dis. (2017)

LASSI-L in Diverse Cultural Populations

Semantic intrusion error ratio distinguishes between cognitively impaired and cognitively intact African American older adults.

Capp et. Al J Alzheimers Dis. (2019)

LASSI-L in Diverse Cultural Populations

A Cognitive Stress Test for prodromal Alzheimer's disease: Multi-ethnic generalizability.

Curiel et. al Alzheimer’s Dement (Amst) (2019)

LASSI-L™: Original paper & pencil based research-focused cognitive challenge test.

LASSI-BC™: Initial research-focused computerized version of the LASSI-L.

LASSI-D™: Brief fully self-administered commercial digital version of the LASSI-L (under the supervision of a healthcare professional).